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Melatonin 

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Melatonin is a generalized hormone that is formed in the brains's pineal gland. The body's own production of melatonin is greatest at the age of 6, declines drastically at puberty, and then diminishes with age.

The Secretion of Melatonin is regulated by daylight. When light strikes the retina of the eye, nerve impulses are transmitted to the pineal gland that, in turn, transforms this information into a hormonal signal in the form of a nocturnal secretion of Melatonin. The body's inner clock is thus regulated, and the REM (Rapid Eye Movement) sleep that is so important to us all increases. Melatonin is therefore used to treat a variety of disturbances in circadian rhythm, such as jet lag.

Melatonin is also a powerful antioxidant that, apart from all its other properties, increases the uptake of other antioxidants. Melatonin can activate the immune system's T-lymphocytes, can reduce inflammtions, increases blood platelet count and diminishes the production of oestrogen that many tumours depend on. Melatonin is also capable of enhacing the effect of chemotherapy and reducing its deleterious side effects.

The size of the doze required varies greatly. Cancer patients will often need 15-25 mg per day. The recommended dose for people suffering from jet lag is 1 mg per time zone passed. It should be administered one hour before midnight!  

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